In today's fast-paced world, stress has become a ubiquitous part of life. While the body is equipped with a stress response system, chronic and prolonged stress can overwhelm this system, leading to a variety of health issues. AdreneVive, by Ortho Molecular Products, is a dietary supplement designed to support the body's stress response, promote adrenal health, and enhance overall well-being. This article delves into the ingredients of AdreneVive, its benefits, and how it stands out from other adrenal support supplements.
Understanding Stress and the HPA Axis
Stress is defined as any disturbance that can trigger the stress response. This includes extreme temperatures, psychological stressors, sleep deprivation, work overload, physical trauma, and exposure to toxins.
The body’s stress response system is comprised of the hypothalamic-pituitary-adrenal (HPA) axis. Prolonged stress triggers the HPA axis and consists of three stages: alarm, resistance, and exhaustion. The initial, short-lived phase is the body’s normal fight-or-flight response to danger which is characterized by elevated cortisol levels. The next phase, the resistance phase, allows the body to continue buffering extended stress exposure, long after the initial fight-or-flight response has dissipated. Hormones released by the adrenals, such as cortisol and DHEA, help support the "resistance" reaction. Extended periods of stress not only burden the system, creating an imbalance in cortisol and DHEA production, but can result in mental and physical fatigue, nervous tension, irritability, and poor memory-all of which are characteristic of stage 3.
AdreneVive is formulated to help respond to HPA axis loading, build stress resilience, and maintain healthy HPA axis function. It provides a unique blend of botanicals and nutrients that support the stress response, particularly promoting cortisol balance during the initial alarm phase, and includes a blend of adaptogenic botanicals and nutrients specifically formulated to counteract the effects of daily stress and support healthy energy levels. AdreneVive provides a unique blend of “stress adapting botanicals” which help increase the body’s resistance to fatigue while helping to maintain balanced cortisol and DHEA levels.
Key Ingredients and Their Benefits
AdreneVive combines several key ingredients known for their adaptogenic and stress-reducing properties. These include:
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L-Theanine
L-theanine is an amino acid found abundantly in green tea. L-theanine has been shown to quickly improve stress perception and resilience. The stress-buffering mechanisms of L-theanine have been connected to the ability of L-theanine to increase serotonin and dopamine production in the brain. L-theanine has also been shown to significantly increase alpha brain wave activity, which is critical for increasing attention as well as promoting a sense of relaxation.
In a study using 16 healthy volunteers, electroencephalograph (EEG) readings of participants were recorded following the ingestion of 50 mg of L-theanine. The researchers found a greater increase in alpha brain wave activity versus placebo. L-theanine has also been shown to have a protective effect for nerve cells and reduces excitatory glutamate activity in the brain.
Phosphatidylserine
Phosphatidylserine is a phospholipid that is found in high concentrations in the brain. Administration of phosphatidylserine has also been studied in exercising subjects. It has been demonstrated that phosphatidylserine reduces the cortisol response to overtraining resulting in a reduction in perceived muscle soreness and improvement in athletic performance.
Ashwagandha Root Extract
Ashwagandha’s strong adaptogenic properties provide an array of benefits for individuals that have compromised health due to extreme stress exposure. Ashwagandha’s benefits include improving stress resilience, supporting immune response, regulating the sleep cycle, supporting healthy thyroid function and protecting against exhaustion of the nervous system. Ashwagandha has also been shown to be beneficial in supporting proper mood regulation and restoring a sense of calmness under stress.
Rhodiola Rosea Root Extract
Rhodiola rosea has been categorized as an adaptogenic botanical due to its ability to increase resistance to a variety of stressors. Rhodiola has been studied extensively and is widely used in Eastern Europe and Asia to help support the nervous system, mood regulation, mental clarity, work performance and the sleep cycle. Within the central nervous system, Rhodiola has demonstrated an ability to preserve levels of neurotransmitters such as serotonin, dopamine and norepinephrine.
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In a randomized, double-blind, placebo-controlled study examining the effects of Rhodiola on fatigue and stress, 161 patients aged 19 to 21 years received Rhodiolatwice daily resulting in a significant reduction in fatigue. An additional study using Rhodiola extract in students showed significant improvements in mental performance, greater mood stability, and improved sleep patterns.
Eleuthero Root Extract
Eleutherococcus senticosus has also been identified as a strong adaptogenic botanical and is widely used in China to improve general health, support memory and endurance. In addition to its ability to improve stress resilience and fight fatigue, Eleuthero has exhibited immune supporting effects.
In a double-blind study, 45 healthy volunteers received Eleuthero or placebo for 30 days. A cognitive challenge test was given to assess stress response, along with heart rate. Unlike placebo, subjects receiving Eleuthero demonstrated a 40% reduction in heart rate in response to the stressor. Eleuthero has also been shown to improve performance in runners. In a study on performance athletes, Eleuthero extract (2 or 4 mL) given 30 minutes prior to a race significantly reduced race time (48.7 minutes) compared to the control group (52.6 minutes).
Skullcap Root Extract
Native to China and parts of Russia, Skullcap root (Scutellaria baicalensis) has been used in traditional Chinese medicine for its immune supporting properties. S. baicalensis has flavanoids which provide numerous protective effects including antioxidant activity and protection against pathogens. Skullcap root has also been shown to balance inflammatory compounds and protect against free radicals that cause lipid oxidation.
How AdreneVive Stands Out
In the crowded market of adrenal support supplements, AdreneVive by Ortho Molecular Products stands out due to its comprehensive formula and high-quality ingredients. Adrenevive's formula includes a blend of adaptogens, vitamins, and nutrients designed to support adrenal function and reduce stress.
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- Comprehensive Formula: Unlike many single-ingredient supplements, Adrenevive combines multiple ingredients that work synergistically to support adrenal health.
- High-Quality Ingredients: Ortho Molecular Products is known for its commitment to quality. Each ingredient in Adrenevive is carefully selected and tested for purity and potency.
Compared to:
- Single-Ingredient Supplements: Products focusing on one primary ingredient, such as ashwagandha or ginseng, may offer limited benefits.
- Low-Quality Ingredients: Some competitors use lower-quality or less bioavailable forms of ingredients, reducing the supplement's effectiveness.
Recommended Use and Lifestyle Integration
For optimal results, it is recommended to take AdreneVive as directed by your healthcare provider. Generally, the suggested use is two capsules per day, preferably with meals.
In addition to taking AdreneVive, consider incorporating these lifestyle recommendations:
- Exercise: Incorporate moderate physical activity such as yoga, walking, or swimming to help manage stress and support adrenal health. Aim for at least 30 minutes of exercise most days of the week.
- Diet: Maintain a balanced diet rich in whole foods. Focus on foods high in antioxidants, healthy fats, and lean proteins. Include plenty of fruits, vegetables, nuts, seeds, and whole grains.
Who Should Consider AdreneVive?
AdreneVive is designed for individuals experiencing symptoms of adrenal fatigue or chronic stress. The adrenal glands are integral to the body's ability to manage stress. When these glands are overworked due to chronic stress, poor diet, lack of sleep, or other factors, it can lead to a condition known as adrenal fatigue. Adrenevive by Ortho Molecular Products targets these symptoms by nourishing the adrenal glands and helping them recover from the effects of prolonged stress.
Potential Drug Interactions
It is important to consult with a healthcare provider before starting AdreneVive, especially if you are taking medications.
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