Phendimetrazine is a prescription medication primarily used as a short-term aid for weight loss in individuals who are obese or overweight. It is a controlled substance due to its potential for misuse and dependence. It's crucial to store it securely and never share it with others.
What is Phendimetrazine?
Phendimetrazine is commonly used to help people with obesity or people who are overweight lose weight. Phendimetrazine may also be used for other conditions as determined by your health care provider.
How Phendimetrazine Works
Phendimetrazine is thought to help people lose weight by reducing appetite, which may help you want to eat less food. Phentermine works best in combination with a diet program.
Dosage and Forms
Phendimetrazine is available in the following forms and strengths:
- 105 mg extended-release oral capsules
- 35 mg oral tablets
Brand names include Bontril PDM, Melfiat, and Plegine.
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Storage Instructions
Phendimetrazine should be stored at room temperature, between 68°F to 77°F (20°C to 25°C). It can be exposed to temperatures between 59°F to 86°F (15°C to 30°C) for shorter periods of time, such as when transporting it. Store in a cool, dry place and protect from moisture.
Common Side Effects
The most common side effects of phendimetrazine are related to its mild stimulant effects (increased blood pressure or heart rate, tremors, trouble sleeping). Tell your health care provider if you have any of these side effects that bother you:
- Feeling of skipped heartbeats
- Fast heartbeat
- High blood pressure
- Feeling restless
- Dizziness
- Trouble sleeping
- Tremors
- Sweating more than usual
- Headache
- Dry mouth
- Nausea
- Diarrhea
- Increased urination
There may be other side effects of phendimetrazine that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
Serious Side Effects
While less common, the most serious side effects of phendimetrazine are described below, along with what to do if they happen.
- Pulmonary Hypertension: Phendimetrazine may increase your risk of developing pulmonary hypertension (high blood pressure in the blood vessels between your heart and your lungs), which can be life-threatening. The risk may be higher in those taking the medicine for longer periods. Stop taking phendimetrazine and get help right away If you have any of the following symptoms:
- Trouble breathing
- Chest pain
- Fainting
- Swelling in your legs
- Heart Valve Problems: Phendimetrazine or medicines like it may rarely cause problems with your heart valves, which can be serious. Stop taking phendimetrazine and get help right away if you have any of the following symptoms:
- Unusual shortness of breath
- Feeling of skipped heartbeats
- Chest pain
- Swelling in the legs
- Fainting or feeling dizzy
- Severe Allergic Reactions: Phendimetrazine may cause allergic reactions, which can be serious. Stop taking phendimetrazine and get help right away if you have any of the following symptoms of a serious allergic reaction:
- Breathing problems or wheezing
- Racing heart
- Fever or general ill feeling
- Swollen lymph nodes
- Swelling of the face, lips, mouth, tongue, or throat
- Trouble swallowing or throat tightness
- Itching, skin rash, or pale red bumps on the skin called hives
- Nausea or vomiting
- Dizziness, feeling lightheaded, or fainting
- Stomach cramps
- Joint pain
Warnings and Precautions
Contraindications
Phendimetrazine is not suitable for everyone. It's crucial to be aware of the following contraindications:
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- Allergies: People who are allergic to any of the following should not take phendimetrazine:
- Bontril PDM
- Melfiat
- Plegine
- Phendimetrazine
- Any other medicine known as a sympathomimetic
- Any of the ingredients in the specific product dispensed
- Heart Conditions: Phendimetrazine should not be used by those with a history of heart attack, stroke, or heart failure.
- High Blood Pressure: Phendimetrazine should not be used by those with uncontrolled high blood pressure.
- Pulmonary Hypertension: Phendimetrazine should not be used by those with pulmonary hypertension.
- Thyroid Problems: Phendimetrazine should not be used by those with an overactive thyroid, also known as hyperthyroidism.
- Agitation: Phendimetrazine is not for people who feel restless, uneasy, nervous, or cranky. These feelings can be caused by stress and certain medical problems.
- Substance Use Disorder: Phendimetrazine should not be used by those with a history of substance use disorder.
- Eye Problems: Phendimetrazine should not be used by those with glaucoma.
- Pregnancy: Do not take phendimetrazine if you are pregnant. If you become pregnant, contact your health care provider right away. See the Pregnancy section for more details. Weight loss during pregnancy can harm an unborn baby, even if you are overweight.
- Breastfeeding: Do not take phendimetrazine if you are breastfeeding. You must stop either breastfeeding or phendimetrazine. See the Breastfeeding section for more details.
- Drug Interactions: Phendimetrazine should not be taken while you are using certain other medicines. Before taking phendimetrazine, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.
Important Considerations Before Use
- Do not take phendimetrazine unless it has been prescribed to you by a health care provider. Take it as prescribed.
- Do not share phendimetrazine with other people, even if they have the same condition as you. It may harm them.
- Keep phendimetrazine out of the reach of children. Phendimetrazine is a controlled substance because it can be misused or lead to dependence. Store phendimetrazine in a safe place to protect it from theft. It is illegal to sell or give away this medicine.
- Phendimetrazine can affect your alertness or coordination. Do not drive or do other activities that require alertness or coordination until you know how phendimetrazine affects you.
- Phendimetrazine is usually only taken for a few weeks. This medicine may be habit-forming and has a risk of being misused. Do not increase your dose, take it more often, or use it for a longer time than prescribed.
- Do not stop using this medicine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using this medicine .
Disclosing Medical History
Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if phendimetrazine is right for you.
In particular, make sure that you discuss any of the following:
- Heart disease, heart murmur, or heart valve problems
- Abnormal heart rate or rhythm
- High blood pressure, including pulmonary hypertension
- Glaucoma
- Thyroid problems
- Diabetes
- Mental health problems, including substance use disorder
- Use of another weight loss medicine or supplement within the last year
- Kidney problems
- Pregnancy or plans to become pregnant
- Breastfeeding or plans to breastfeed
Interactions
Food and Drink Interactions
The immediate-release tablet should be taken one hour before meals. The extended-release capsule should be taken 30 minutes to one hour before the morning meal.
The risk of dizziness may be increased if you drink alcohol while taking phendimetrazine.
Drug Interactions
Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
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In particular, make sure that you discuss if you are using any of the following before taking phendimetrazine:
- Linezolid (Zyvox), which is a medicine used for certain bacterial infections
- A monoamine oxidase inhibitor (MAOI) within the past two weeks, which is a medicine usually used for depression or Parkinson’s disease
- A medicine or supplement for weight loss
- A medicine for high blood pressure
- A medicine for diabetes
This may not be a complete list of medicines that can interact with phendimetrazine. Always check with your health care provider.
Additional Information
- Phendimetrazine is a controlled substance. It is illegal to sell or give away this medicine.
- Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital.
- Follow the diet and exercise program your doctor has given you.
PhenRx: An Alternative
PhenRx is another non-prescription Phentermine-alternative brand that is known for its powerful weight loss formula.
Like its competitors Phen375, PhenObestin, Adiphene and many others, PhenRx claims that it can offer various areas of weight loss, that are seldom offered by other dietary supplement brands that can be found online.
If you are overweight or an obese individual, then you truly need a diet pill that will help support your overall weight loss program. This pharmaceutical company offers various type of products ranging from slimming and nootropics, to general health and beauty supplements. PhenRx is a sister product of the equally successful diet pill - SlenderFruit-7.
Claimed Benefits of PhenRx
- It targets fat and lipid metabolism on stubborn problem areas
- Increases your metabolic rate, fat burning and improved lean body mass
- Powerful 24-hour appetite suppressing benefit
- Boosts energy and mental focus
How PhenRx Works
PhenRx works by reducing your cravings two folds compared to other hyped dietary pills in the market.
NexGen Biolabs claims that PhenRx is one of the most powerful appetite suppressant formula that can stop food cravings and makes dieting an easy task. If you can manage your diet more effectively, then it will help curb your cravings that will results to natural weight loss.
This supplement is also designed to help burn those stubborn fatty areas of your body such as skin cellulite, stomach, thighs and many others. The brand’s potent ingredients can help trigger fat loss on these fatty areas that will help reveal your sexy physique.
Plus, the manufacturer of this supplement claims that it won’t burn muscle tissues, making it a perfect supplement for your workout and other sports activities.
Ingredients of PhenRx
- Trimethylxanthine
- Beta-Phenylethylamine
- Synephrine HCL
- N-Dimethyl-4-hydroxyphenylethylamine
- Schizandrol A
- Yohimbe HCL
Inactive ingredients include magnesium stearate and silicon dioxide.
Potential Side Effects of PhenRx
Since this brand is packed with caffeine, it is obvious that PhenRx is NOT a side effect-free diet pill.
Some of my readers reported some adverse health effects that include headache, jitters, insomnia and many others. These effects are actually common in most products that contains caffeine, and PhenRx is not an exemption.
If you are not allergic to caffeine, then you have less to worry about these reported side effects.
Directions of Use
Like any other appetite suppressants, NexGen Biolabs recommend that you take 1 capsule before lunch and another capsule before dinner. You should not exceed this serving per day as it can interfere with your health due to stimulants.
Again, it is advisable to consult your physician first before taking any phentermine alternative products such as PhenRx, especially if you have existing health conditions such as hypertension, diabetes, pregnancy or if you are under the age of 19 years.
This is to ensure that your diet pill supplementation will not trigger any adverse health effects but only desirable weight loss.
Pros of PhenRx
- Natural formula
- Some favorable reviews online
- May help trigger significant weight loss
- Money-back guarantee
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