Keto IQ Supplement: Ingredients, Benefits, and Scientific Evaluation

The increasing popularity of the ketogenic diet has led to a surge in keto supplements, promising enhanced results. Among these, Keto IQ supplements have gained attention. This article delves into the ingredients, purported benefits, and scientific backing of Keto IQ supplements, providing a comprehensive overview for those considering their use.

Understanding Ketosis and Ketones

Before diving into Keto IQ, it's crucial to understand ketosis and ketones. Ketosis is a metabolic state where the body primarily uses fat for fuel instead of carbohydrates. This occurs when carbohydrate intake is restricted, prompting the liver to produce ketones from fatty acids. These ketones then serve as an alternative energy source, especially for the brain.

There are two ways to raise your ketones:

  • Endogenous ketosis: Your body makes the ketones through a process called ketogenesis. To get into endogenous ketosis, people engage in endurance exercise, follow low-carb/"keto" diets, or fast/starve. These activities cause blood glucose levels to drop and deplete glycogen (sugar) stores. Your body responds to the dip in energy by ramping up ketogenesis, or the breakdown of fat to make ketones to use for energy.
  • Exogenous ketosis: The ketones come from outside your body, e.g. Ketone-IQ or other ketone supplements.

What is Keto IQ?

Ketone-IQ is a ketone supplement containing a pure 100% Ketone Diol called R-1,3-Butanediol (R-1,3-BDO). R-1,3-BDO is the closest precursor to D-BHB, and it's converted directly into D-BHB with near 100% efficiency.

Ingredients of Keto IQ Supplements

The primary active ingredient in Keto IQ is typically R-1,3-Butanediol (R-1,3-BDO), a ketone diol. Other ingredients may include:

Read also: The role of alpha-keto acids in metabolism.

  • Electrolytes: Sodium, magnesium, or calcium, which are often added to ketone supplements to replenish those lost during ketosis.
  • Flavorings and Sweeteners: To improve the taste and palatability of the supplement.

Purported Benefits of Keto IQ Supplements

Keto IQ supplements are marketed with several potential benefits:

  • Improved Cognitive Function: Ketones are an ultra-efficient fuel, especially for our brains. They’re evolutionarily designed to keep us razor-sharp and at peak performance between meals. Ketones can cross the blood-brain barrier and generate 28% more ATP per gram than glucose. As an ultra-efficient brain fuel, they’re proven to improve focus, cognitive, and mental clarity and protect the brain from trauma, aging, and neurodegenerative diseases.
  • Enhanced Physical Performance: When you’re thinking sharper, you can perform better. Ketones can improve athletic performance by enhancing cognition, resulting in better reaction times and reduced fatigue. Plus, ketone supplements can support endurance and recovery for athletes; one study found that drinking ketones during a 3-week overtraining period led to a 15% increase in power output.
  • Metabolic Health and Appetite: Ketones, and raising your blood ketone levels, have been shown to significantly reduce ghrelin (1), the hunger hormone.
  • Faster Ketosis: Exogenous ketones can quickly raise blood ketone levels, potentially easing the transition into ketosis.
  • Appetite Suppression: Some studies suggest that ketone supplements may help reduce hunger and cravings.
  • Increased Energy: Ketones can provide an alternative fuel source, potentially boosting energy levels.

Scientific Evidence and Research

The scientific community has been actively researching the effects of exogenous ketone supplements on various aspects of health and performance. However, the findings are mixed and often contradictory.

  • Cognitive Performance: Case reports, a small trial in athletes, and animal studies indicate that including exogenous BHB in the diet can improve cognitive performance.
  • Exercise Performance: The research on exogenous ketones supplementation for exercise performance, however, indicates that they can have either a negative effect, a net benefit, or no significant effect. At this point, the research indicates that taking a BHB ketone ester with carbohydrate prior to exercise provides most significant, yet still incremental, increase in performance compared to other exogenous ketone supplement dosing strategies.
  • Endurance: A seminal study reported an improvement in simulated endurance bicycling performance with acute administration of ketone esters along with carbohydrates in trained athletes, as reflected by a slight increase in the total distance covered during a fixed time compared with the administration of carbohydrates alone.However, subsequent studies have failed to replicate performance benefits with acute ketone supplementation and some authors have in fact reported decrements in performance.

Systematic Review Findings:

A large systematic review of this subject was published in the Journal of Frontiers in Physiology in March of 2020. They reviewed 10 different studies including 112 participants. They looked at a variety of ketone products such as ketone esters, ketone precursors, and ketone salts. The review included 16 different measurements for physical performance; 8 for lower body power & 8 for endurance.

The results showed that 13 of the performance measurements resulted in no change in performance, 3 of the performance measurements resulted in performance improvements, and 3 showed performance impairments. In other words, the data were perfectly equivocal.

  • Power Output: Across all the studies looking at mean or maximum power capacity with ketone supplementation, there are 4 showing improvements and 4 showing performance impairments.
  • Endurance: There are currently 8 studies looking at how ketone supplementation improves endurance performance. 5 of them show performance impairments, 3 of them show performance improvements.

Important Considerations:

  • Study Limitations: Many studies have small sample sizes, varying methodologies, and different types of ketone supplements, making it difficult to draw definitive conclusions.
  • Individual Variability: The effects of ketone supplements can vary significantly from person to person.
  • Keto-Adaptation: The benefits of ketones may be more pronounced in individuals who are already keto-adapted (i.e., following a ketogenic diet for an extended period).

Potential Side Effects

While generally considered safe for most people, Keto IQ supplements can cause side effects, especially when starting:

Read also: Ultimate Keto Dressing Guide

  • Digestive Issues: Ketone salts, in particular, can cause digestive discomfort, including nausea, diarrhea, and stomach upset, due to their high salt content.
  • Electrolyte Imbalance: Exogenous ketones can affect electrolyte balance, potentially leading to muscle cramps or heart palpitations.
  • Keto Flu Symptoms: Some individuals may experience keto flu symptoms, such as fatigue, headache, and dizziness, when starting ketone supplementation.

Keto IQ vs. Other Ketone Supplements

There are several types of ketone supplements available:

  • Ketone Salts: These are ketone bodies bound to minerals like sodium, potassium, or calcium. They are the most accessible and widely available form.
  • Ketone Esters: These are ketones linked to an ester compound, typically in liquid form. They are more potent at raising blood ketone levels but often have a bitter taste and can be more expensive.
  • MCT Oil: Medium-chain triglycerides (MCTs) are fats that are easily converted into ketones by the liver. MCT oil is a more indirect way to boost ketone production.
  • Ketone Diol (Ketone-IQ): Through our $6MM contract with the United States Department of Defense Special Operations Command (US DOD SOCOM), we found that Ketone Diols are ideal for physically and cognitively demanding tasks, unlike HVMN Ketone V1, which was a Ketone Ester.

Comparison:

Supplement TypeProsCons
Ketone SaltsWidely available, relatively inexpensiveCan cause digestive issues, less effective at raising ketone levels
Ketone EstersMore effective at raising ketone levelsExpensive, unpleasant taste, may cause nausea
MCT OilSupports natural ketone production, may aid fat burningCan cause digestive issues if taken in large amounts
Ketone DiolIdeal for physically and cognitively demanding tasks, Fast ActingMay not be as widely available as other options, more research may be needed to confirm benefits

Dosage and Usage

The appropriate dosage of Keto IQ supplements can vary depending on the product and individual factors. It's essential to follow the manufacturer's instructions. A common recommendation is to start with a lower dose and gradually increase it to assess tolerance.

  • Timing: Keto IQ can be taken before exercise, during periods of mental exertion, or as directed by a healthcare professional.

Is Keto IQ a Scam?

One of the biggest problems with the fitness & supplement industry is that it’s filled with great marketers who don’t know a thing about exercise science or nutrition.Ketone-IQ is a prime example of such a company.

Claim 1: “28% more efficient in generating energy than glucose alone”

Their source for this claim is a 1995 study done in rats. The researchers did find that when the glucose was combined with insulin & ketone bodies, more energy was produced than with glucose alone. However, this isn’t at all relevant for three reasons:

  • You likely aren’t injecting insulin
  • You aren’t a rat with mitochondrial damage
  • You can’t draw conclusions for humans done off mechanism or rodent studies

Claim 2: “15% Mean power output improvement after recovery”

This was a good study, but it doesn’t conclusively show that ketones are all high-and-mighty. Here’s why:

Read also: Bake Perfect Keto Bread Every Time

  • The study wasn’t looking to see if ketones improve performance, just how they impact markers of functional overreaching.
  • There was no baseline testing for the 120 minute test, and performance in various time durations are specific. So, you can’t really say whether or not the improvement was a result of the ketone supplements or inherent to the subjects.
  • The subjects in the ketone group had better average performances on the 30 minute & 120 minute trial, but the control group performed better on average in the 90-second sprints.
  • The ketone ester group consumed much more calories on average, which is also a big contributor to physical performance.
  • Across all the studies looking at mean or maximum power capacity with ketone supplementation, there are 4 showing improvements and 4 showing performance impairments.

Bottom line: this study, and the research overall, does NOT conclusively show that ketones improve mean power production.

Claim 3: “2% improved athlete’s endurance”

This study sparked much of the initial interest in ketone supplementation, however other studies have yielded different results.

There are currently 8 studies looking at how ketone supplementation improves endurance performance. 5 of them show performance impairments, 3 of them show performance improvements.

So, although this study showed endurance performance improvements, the overall body of research shows otherwise.

What HVMN’s Ketone-IQ has done here is something many other snake-oil companies do: cherry-pick the studies that support their product while ignoring the rest of the research.

The systematic review I previously cited [9] reviewed all the available data including 16 different performance outcomes. 10 showed no effect, 3 showed performance improvements, and 3 showed performance impairments.

Based on this, you clearly can’t say for certain whether there’s a benefit to be had or not.

Who Might Benefit from Keto IQ?

While the research is still evolving, certain individuals might find Keto IQ supplements helpful:

  • Athletes: Especially endurance athletes, who may experience improved performance or recovery.
  • Individuals Starting a Keto Diet: To help ease the transition into ketosis and reduce keto flu symptoms.
  • People Seeking Cognitive Enhancement: Those looking for a mental boost in focus and clarity.
  • People who have health conditions that benefit from ketosis, but cannot stay on the keto diet for any reason.

Supplementing with MCT Oil: A Cheaper Alternative

Fortunately, there is a ketone-boosting supplement that actually supports ketosis and ignites fat burning: MCT oil.

MCT stands for medium chain triglycerides - a type of saturated fat that skips the normal digestive process of other fats. This influx of MCTs into the liver mimics the process that occurs when fatty acids are released from our fat cells and enter the liver during carb restriction. By supplementing with MCTs rather than exogenous ketones, you are giving the liver the substrates it needs to jump start ketosis without shutting down ketone production.

The research on MCT supplementation is more extensive and convincing than what we’ve found to support exogenous ketones as well.

Overall, the research indicates that MCTs are equally, if not more, beneficial than exogenous ketone supplements.

When we consider this with the current literature and our bank accounts, MCT oil supplements still seem to be the best ketone supplement available.

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