Thermogenic supplements are widely used in the general population to support attempted fat loss; however, the efficacy and safety of the variety of ingredient blends in such supplements are questioned. EHPlabs is renowned for its flagship product, OxyShred, which caters to all levels of activity, training experience, and fitness goals. OxyShred is formulated not only to promote fat burning but also to provide immune support, reduce cravings, and enhance focus. Millions of people have successfully transformed their body composition with the help of OxyShred, alongside a balanced diet and regular exercise.
Understanding OxyShred and Its Variants
OxyShred is formulated with a powerful blend of ingredients designed to stimulate your body’s fat receptor cells and boost metabolism, promoting an increased breakdown of fat cells.
EHPlabs offers several variants of OxyShred to cater to different preferences and sensitivities:
OxyShred Ultra Concentration: This version features a balanced blend of mild stimulants like caffeine anhydrous and a full spectrum of B-vitamins. This combination delivers a morning energy boost and sustains energy levels throughout the day. Enhanced with mood-boosting ingredients such as tyrosine, taurine, and huperzine A, it promotes powerful focus, alertness, and concentration.
OxyShred Hardcore: For those seeking an extra edge, OxyShred Hardcore delivers an intense energy surge. With increased amounts of stimulants like caffeine anhydrous, guarana seed extract, and green coffee bean extract, this variant provides longer-lasting, smoother energy. OxyShred Hardcore is particularly effective as a pre-workout due to its higher stimulant content.
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OxyShred Non-Stim: OxyShred Non-Stim is ideal for those sensitive to stimulants. It retains the potent fat-burning ingredients of OxyShred Ultra Concentration but removes stimulants like caffeine anhydrous, bitter orange fruit extract, and green coffee bean. Instead, it incorporates Theacrine, a compound from coffee beans and tea leaves that offers clean, natural energy by enhancing oxygen uptake without affecting the adrenal glands, central nervous system, heart rate, or blood pressure.
To maximize fat loss, consider adding OxySleep to your routine. This non-stimulant nighttime supplement features ingredients that promote fat burning while improving sleep quality and increasing time spent in deep sleep.
Key Ingredients and Their Roles
OxyShred contains a variety of ingredients, each with a specific role in promoting weight loss and enhancing energy levels. Here's a closer look at some of the key components:
Caffeine: Caffeine is often the main ingredient in commercially available thermogenic supplements due to its ability to increase resting energy expenditure (REE) as well as augment fat oxidation and fatty acid turnover both at rest and during exercise.
Acetyl L-Carnitine HCl and Conjugated Linoleic Acid (CLA): These ingredients work more effectively when your body isn't busy digesting food, enhancing fat-burning processes.
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Garcinia Cambogia, CLA, green coffee bean extract, olive leaf extract, and chromium picolinate: One of the biggest challenges in losing weight is managing hunger and cravings. OxyShred's unique blend of these ingredients works synergistically to suppress appetite and curb hunger pains.
Chromium Picolinate: Chromium picolinate, in particular, helps balance blood sugar levels and reduce insulin resistance. Chromium Picolinate in OxyShred helps balance blood sugar levels and curb sugar cravings.
Scientific Evaluation of OxyShred's Effectiveness
To evaluate the efficacy of OxyShred, a study was conducted using a randomized, double-blind, placebo-controlled crossover design. The participants in this study were healthy female college students (22.2 ± 3.5 years; 164.8 ± 6.4 cm; 73.5 ± 6.9 kg) between the ages of 18-40 with a body mass index (BMI) between 25 and 32.5 kg*m2 and were selected from a pool of volunteers. In a randomized double-blind crossover design, 23 females (22.2 ± 3.5 years; 164.8 ± 6.4 cm; 73.5 ± 6.9 kg) who were moderate caffeine consumers (<150 mg/day) reported to the lab after a 12 h fast for baseline assessments of resting energy expenditure (REE) via indirect calorimetry, heart rate (HR), blood pressure (SBP and DBP), blood variables, and hunger, satiety, and mood states. Thereafter, subjects ingested the assigned treatment (active treatment containing caffeine, micronutrients, and phytochemicals [TR] or placebo [PL]). All variables were reassessed at 30-, 60-, 120-, and 180 min post-ingestion. Subjects repeated the same protocol with ingestion of the opposite treatment on a separate day.
Impact on Resting Energy Expenditure (REE)
The study revealed that the active treatment (TR) significantly increased REE compared to the placebo (PL). In the TR group, mean increases in REE of 121 to 166 kcal/d were observed at 30-, 60-, and 180 min post-ingestion (p < 0.01 for all). In contrast, the PL group mean decreases in REE of 72 to 91 kcal/day were observed at 60-, 120-, and 180 min (p < 0.05 for all). Follow-up testing with a paired samples t-test revealed a significant increase in REE after ingesting TR from baseline to 30, 60, 120, and 180 min (p < 0.001, p = 0.001, p = 0.049, p = 0.001, respectively), and significant decreases in REE after ingesting PLA from baseline to 30, 60, 120, and 180 min (p = 0.042, p = 0.001, p = 0.007, p = 0.02).
Effects on Respiratory Quotient (RQ)
Respiratory quotient decreased at 120 and 180 min in both treatments. No condition*time interaction (F = 0.844, p = 0.495, ηp2 = 0.037) was observed for RQ. A significant main effect for time (F = 8.757, p = 0.000, ηp2 = 0.285) but not condition (F = 0.701, p = 0.412, ηp2 = 0.031) was observed for RQ.
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Changes in Blood Pressure and Heart Rate
Slight increases in SBP of 3-4 mmHg were observed at 30, 120, and 180 min (p < 0.05 for all) post-ingestion of TR, while no effects were observed for DBP. Observed increases in SBP were within normal blood pressure ranges. A significant condition*time interaction (F = 3.156, p = 0.019, ηp2 = 0.131) as well as a main effect for condition (F = 10.367, p = 0.004, ηp2 = 0.330) was observed for SBP. There was no observed main effect for time (F = 1.110, p = 0.355, ηp2 = 0.050) for SBP.
Impact on Fatigue and Mood States
TR decreased subjective fatigue with no other significant changes in mood states. A significant condition*time interaction was observed (F = 3.042, p = 0.037, ηp2 = 0.121) for subjective levels of focus. There was a significant main effect for time (F = 8.043, p < 0.001, ηp2 = 0.268) but not condition (F = 0.467, p = 0.502, ηp2 = 0.021).
Effects on Glycerol and Free Fatty Acids
Glycerol was maintained in TR, while there was a decrease at 30, 60, and 180 min (p < 0.05 for all) post-ingestion of PLA. Free fatty acids increased in TR at 60 and 180 min (p < 0.05) post-ingestion as well as a significant difference between treatments at 30 min post-ingestion indicating greater circulating free fatty acids levels in TR vs.
How to Maximize OxyShred's Effectiveness
OxyShred is best consumed first thing in the morning before food. This practice maximizes the absorption and effectiveness of its caffeine-containing ingredients, which provide a faster energy boost when taken on an empty stomach. However, it's crucial to remember that effective fat loss requires a calorie-reduced diet and regular exercise.
Addressing Common Questions and Concerns
If you’ve ever wondered, "Does OxyShred actually work?" the answer is a resounding yes! However, it's crucial to remember that effective fat loss requires a calorie-reduced diet and regular exercise. Stimulant-based supplements often raise concerns for the potential negative impact on hemodynamic variables such as heart rate (HR) and blood pressure (BP). Of the available literature on thermogenic supplements and their impact on metabolic rate and hemodynamic responses, the outcomes seem to be contradictory in the magnitude at which the effect is observed. Furthermore, the safety and efficacy of specific, commercially available multi-ingredient supplements must be evaluated.
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