The Leptin Diet: Meal Plan Guidelines, Benefits, and Risks

The leptin diet is designed to optimize leptin levels within your body using low carbohydrates and eating windows in an effort to reduce leptin resistance. This eating plan is considered a fad diet, and there is currently a lack of research supporting its effectiveness. Fad diets often promote quick weight loss that is unsustainable and may severely restrict what you eat. They may be harmful and generally do not have long-lasting health benefits. Before starting any diet, it is important to talk with your healthcare provider about its safety and your own personal health needs.

Understanding Leptin

Leptin, discovered in 1994, is a hormone produced in the fat stores of your body. It is secreted by fat cells and influences how fat is stored in the body and burns energy. Leptin is also called the satiety hormone because it regulates hunger and reduces appetite. Leptin travels through your bloodstream to the part of your brain that controls appetite. Its job is to signal your brain when you’re full, triggering you to stop eating. It also binds to receptors that signal when you’re full, helping to reduce hunger.

Leptin also supports efficient metabolism. It regulates energy levels by maintaining a balance between hunger and appetite. The hormone triggers the body to respond by eating more when energy levels are low and eating less when energy levels are stable or high.

Leptin Resistance and Deficiency

When too much leptin builds up in your blood, it can lead to leptin resistance. This means leptin becomes less effective, often causing weight gain. If you have leptin resistance, your brain doesn’t respond as it normally would to leptin. Since leptin constantly stimulates your brain, you don’t get the sensation of feeling full. This causes you to eat more even though your body has enough fat stores. The seeming lack of leptin also causes your body to enter starvation mode. To save energy, your brain decreases your energy levels and makes you use fewer calories at rest; in other words, it lowers your basal metabolic rate (BMR). So, leptin resistance makes weight gain worse by making you feel hungry and lowering your BMR.

Having obesity results in high levels of leptin (hyperleptinemia). Other conditions associated with hyperleptinemia include constantly feeling hungry (hyperphagia) and increased food intake.

Read also: Leptin Resistance

It’s very rare to have leptin deficiency (hypoleptinemia). The main condition associated with it is congenital leptin deficiency. It’s a genetic condition you’re born with that prevents your adipose tissue from making leptin. Without leptin, your body thinks it has no body fat. This signals intense, uncontrolled hunger and food consumption. Leptin injections are a way of reducing this problem.

The Leptin Diet: How It Claims to Work

The leptin diet was developed by Mary Richards and Byron J. Richards, a board-certified clinical nutritionist. Richards’ company, Wellness Resources, manufactures herbal supplements designed to support the leptin diet. He’s also written several books about leptin and its role in weight loss and health.

The leptin diet focuses on several key elements to optimize leptin levels, including:

  • Eating foods high in protein, especially at breakfast. Eating a breakfast rich in protein can help you avoid energy slumps, food cravings, and blood sugar spikes. If you eat more protein than carbs, your body will burn considerably more calories.
  • Reducing carbohydrate intake. While carbs are important for a balanced diet, most diets include too many. Unused carbs are stored as fat. Instead of eliminating carbs, consume them in healthy amounts.
  • Limiting yourself to three meals per day, with no snacking in between meals. Allows for five to six hours to pass between each meal. During the first three hours following a meal, the hormone insulin stores all the calories from the food you eat and puts your body into glucose-burning mode. Your body enters a fat-burning state between four to six hours.
  • Finishing the last meal of your day at least three hours before bed. Your body heals itself while you sleep, and leptin plays a crucial role in this process. Leptin helps release important hormones, including sex, growth, and thyroid hormones. The body burns calories consumed during the day for the first six to eight hours after eating dinner. The most efficient fat-burning period is between the 8th and 12th hour after dinner.
  • Eliminating large meals. Practice portion control at each meal. Don’t eat until you are stuffed. Stop before you feel completely full. It takes your brain roughly 20 minutes to recognize that your stomach is full. So, eat slowly and stop while you are ahead to keep your body from creating too many leptins and becoming leptin resistant. Another strategy is to take a five-minute rest after you have finished half of your meal.

The leptin diet hopes to optimize leptin levels in the body so you can better control how much food your body signals you to eat. It emphasizes the need for portion control. These recommendations represent sound nutritional advice. The leptin diet is also accompanied by easy-to-maintain exercise guidelines, which don’t require you to work out endlessly in order to lose weight. When combined with portion control and nutritious food choices, regular exercise may help you lose weight.

The leptin diet requires you to control when you eat, as well as what you eat. Creating a routine that distracts you between meals, and includes moderate exercise, may help you to stick with the diet and successfully lose weight.

Read also: The Truth About Leptin and Weight Loss

What You Can Eat on the Leptin Diet

The leptin diet recommends consuming a variety of fresh, organic foods to limit chemicals or additives. It also suggests that your daily diet should be made up of 40 percent fat, 30 percent carbohydrates, and 30 percent proteins. Fiber intake is recommended to be between 30 and 50 grams, and you’re advised to have 8 to 16 ounces of water in between meals.

Foods to Include

  • Lean proteins, like chicken, turkey as well as beef without any fats. Maintaining muscles requires lean proteins.
  • Foods rich in omega-3s like salmon, mackerel, and sardines. Fatty fish like salmon, mackerel, and sardines are rich in omega-3 fatty acids. Omega-3s are known to reduce inflammation and improve leptin sensitivity.
  • Fresh fruits and vegetables higher in fiber, including broccoli, brussels sprouts, berries, and greens. Berries such as blueberries, strawberries, raspberries, and others are rich in fiber and antioxidants, help control blood sugar levels, and encourage the creation of leptin in a healthy way. Broccoli is rich in fiber. The fiber in broccoli contains sulforaphane, which boosts metabolism. Leafy greens such as spinach and kale are rich in nutrients while containing a few calories.
  • Whole grains such as brown rice, quinoa, and whole wheat contain fiber and complex carbohydrates. They are what produce continuous energy and promote stable levels of glucose in one’s body.
  • Beans, lentils, and chickpeas are notable by reason of their high protein, fiber, and complex carb content. Incorporating these foods into your diet can help optimize leptin function, regulate appetite, and support your overall health and weight management goals.

Other foods that can be included are eggs, red apples, nuts, avocados, legumes, and healthy oils such as canola, olive, or high-oleic sunflower oil. Protein-dense grains and legumes, such as quinoa, oatmeal, and lentils, are also good choices.

Foods to Avoid

  • Soda (regular and diet).
  • Artificial sweeteners.
  • Energy drinks.
  • Processed foods.
  • Foods high in saturated fats, like butter.
  • Foods high in carbohydrates like white bread, pastas, and pastries.
  • Soy products of any kind.

When you’re on the leptin diet, you’re supposed to avoid artificial sweeteners, regular and diet soda, and energy drinks.

Potential Benefits of the Leptin Diet

There is no direct, peer-reviewed research supporting the leptin diet, but the claimed benefits are weight loss and healthier leptin levels overall, which may help brain and metabolic functions.

One study shows that specific diets might have the potential to “recover sensitivity” to the hormone, but many questions still remain. Clinical studies of the benefit of healthy leptin levels have been limited in size and scope and results have been mixed as to its total benefit. A 2021 study suggests that diets high in fat, carbohydrates, fructose, and sucrose and low in protein are drivers of leptin resistance. The researchers concluded that leptin resistance might be reversible by reducing calories. However, this research has some limitations, such as small sample sizes, so further evidence is required to verify these claims.

Read also: The Hoxsey Diet

Importantly, research shows that leptin levels are not directly controlled by short-term diet changes but by weight and food intake over a longer period of time, meaning that a fad diet is unlikely to impact leptin levels anyway. Limiting snacking and shortening your daily eating window could create a calorie deficit necessary for weight loss.

Potential Risks of the Leptin Diet

Like many fad diets, safety and efficacy are important. When certain important nutrients aren’t part of your daily intake due to diet restrictions, other health concerns may arise. Concerns have been raised by the American Academy of Family Physicians (AAFP) regarding the long-term safety and efficacy of low-carbohydrate diets, such as the leptin diet. Such diets may be deficient in essential nutrients and not suitable for those with comorbid conditions.

Since the leptin diet is considered a low-carbohydrate diet, certain nutrients, like fiber, might not be as big of a priority as they should be. This can lead to gastrointestinal symptoms like constipation. A lower carbohydrate intake may lead to gut bacteria changes and/or constipation, so choose high fiber foods as often as possible.

The leptin diet can also be extremely restrictive with regard to when you’re allowed to eat. This can make it difficult to follow the diet and harder to sustain. For example, if you work until close to bedtime, it can be difficult to follow a diet restricting eating before bed.

Is the Leptin Diet Right for You?

While the leptin diet does offer some healthy suggestions like limiting artificial sweeteners and incorporating fruits and vegetables as part of a healthy diet, it’s important to remember that a diet must be sustainable for it to be effective in the long run. The leptin diet may provide you with quick results, but it might not be the long-term diet you’re looking for.

As with any diet plan, it’s best to check with your doctor before starting the leptin diet. It may not provide enough calories if you’re extremely active. It may not be suitable for children or young teens who have different caloric requirements than adults.

Before starting any new diet, it’s essential to consider your personal health goals, lifestyle, and nutritional needs. Everyone’s body is different, so what works for one person may not work for another. Age, pregnancy, breastfeeding, and certain medical conditions influence how many calories your body needs.

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